Cade Skywalker easily defeats Darth Stryfe of the One Sith. Although in this case he did have an assist from Jariah Syn with his explosives, which looks to me like thermal detonators.
Hard to gauge Darth Stryfe’s skill level here, we only have Darth Krayt’s opinion of him, having chosen Stryfe as his Hand to replace Darth Talon and Darth Nihl.
Cade is able to go toe to toe with Darth Talon so it’s not farfetched to assume that he can also deal with Stryfe.
From – Star Wars: Legacy #31